アザ-イソインドロンおよび代謝型グルタミン酸レセプター増強剤-613としてのそれらの使用

Title:

アザ-イソインドロンおよび代謝型グルタミン酸レセプター増強剤-613としてのそれらの使用

Document Type and Number:

Japanese Patent JP2010518104

Kind Code:

A

Abstract:

Compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7, R8 and n are defined in the specification, methods for using said compounds, methods for making said compounds and pharmaceutical compositions containing said compounds.

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Inventors:

Abdelmalik Surashi
Mesvin Isaac
Joshua Clayton
Ian Eggle
Bab joseph
Phu Pen Ma

Application Number:

JP2009549180A

Publication Date:

May 27, 2010

Filing Date:

January 31, 2008

Export Citation:

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Assignee:

ASTRAZENECA AKTIEBOLAG

International Classes:

C07D471/04; A61K31/437; A61K31/496; A61P1/08; A61P9/00; A61P9/10; A61P13/02; A61P21/00; A61P25/00; A61P25/04; A61P25/06; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P27/02; A61P27/16; A61P29/02; A61P31/18; A61P43/00

Foreign References:

WO2005021532A1	2005-03-10
WO2006125180A1	2006-11-23
WO2005056524A2	2005-06-23
WO1998042666A1	1998-10-01

Other References:

JPN5010002943; Ｙ　ＹＡＭＡＭＯＴＯ: ＡＤＶ．　ＳＹＮＴＨ．　ＣＡＴＡＬ．Ｖ３４７, 2005, Ｐ１９１３-１９１６
JPN5010002944; Ｇ　ＤＥＧＵＥＳＴ: ＯＲＧ．　ＬＥＴＴ．Ｖ８　Ｎ２５, 2006, Ｐ５８８９-５８９２
JPN7013000692; Ｃｈｅｍｉｓｔｒｙ--Ａ　Ｅｕｒｏｐｅａｎ　Ｊｏｕｒｎａｌ　（２００６），　１２（２１），　５６１８-５６３１
JPN5010002946; ＰＡＲＣＨＩＮＳＫＹ　Ｖ　Ｚ: ＬＥＴＴＥＲＳ　ＩＮ　ＯＲＧＡＮＩＣ　ＣＨＥＭＩＳＴＲＹＶ３　Ｎ５, 20060101, Ｐ３７９-３８３, ＢＥＮＴＨＡＭ　ＳＣＩＥＮＣＥ　ＰＵＢＬＩＳＨＥＲＳ　ＬＴＤ．
JPN5010002947; Ｒ　Ａ　ＮＡＤＺＨＡＦＯＶＡ: ＲＵＳＳ．　Ｊ．　ＯＲＧ．　ＣＨＥＭ．Ｖ３８　Ｎ１, 2002, Ｐ１２６-１２８
JPN7013000693; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＲＥＧＩＳＴＲＹ，　ＲＮ＝９０４４３５-０８-１
JPN7013000694; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＲＥＧＩＳＴＲＹ，　ＲＮ＝９０４４３５-０７-０
JPN7013000695; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＲＥＧＩＳＴＲＹ，　ＲＮ＝９０２４９８-２１-９
JPN7013000696; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＲＥＧＩＳＴＲＹ，　ＲＮ＝９０２４９７-６７-０
JPN7013000697; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＲＥＧＩＳＴＲＹ，　ＲＮ＝７１０２８４-９４-９
JPN7013000699; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＣＡＰＬＵＳ，　ＡＮ＝２００６：１３４８１４１，ＲＮ＝９１９０９３-５３-１，９１９０９３-５９-７，９１９０９３-６１-１，９１９０９３-６３-３
JPN7013000700; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＣＡＰＬＵＳ，　ＡＮ＝２００５：２７１４９２，ＲＮ＝８６５８６７-６２-５，８６５８６７-６０-３，８６５８６７-６１-４，８６５８６７-６２-５
JPN7013000704; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＣＡＰＬＵＳ，　ＡＮ＝１９９９：６０２９７１，ＲＮ＝２５１１０１-３０-１
JPN7013000705; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＣＡＰＬＵＳ，　ＡＮ＝１９７５：４０９８５４，ＲＮ＝５５７６８-９８-４
JPN7013000701; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＣＡＰＬＵＳ，　ＡＮ＝１９７３：７２０６３，ＲＮ＝４０１０７-９６-８，４０１０７-９８-０
JPN7013000702; ＳＴＮ　ＯＮ　ＴＨＥ　ＷＥＢ，　ＦＩＬＥ　ＣＡＰＬＵＳ，　ＡＮ＝１９６１：８７５１３，ＲＮ＝１０９７２９-３４-２

Attorney, Agent or Firm:

Junji Yuda
Shoji Miwa
Noriyuki Takebayashi

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