Title:
アゾ誘導体およびジアザ誘導体ならびにそれらの光線療法における使用
Document Type and Number:
Japanese Patent JP2011503238
Kind Code:
A
Abstract:
The invention relates generally to optical agents, including Type 1 phototherapeutic agents, for biomedical applications, such as phototherapy. Provided are fused ring azo and diaza compounds comprising a plurality of fused rings including a first ring having an intra-ring azo or intra-ring diaza group capable of activation upon exposure to electromagnetic radiation in visible and/or infrared regions of the electromagnetic spectrum. Optical agents of the invention enable a versatile phototherapy platform for treatment of a range of pathological conditions, including the treatment of cancers, stenosis and inflammation. The invention further provides preparations and formulations comprising the fused ring azo and diaza compounds and methods of making and using the fused ring azo and diaza compounds as optical agents in in vivo or ex vivo biomedical procedures.
Inventors:
Rajagopalan, Ragaban
Application Number:
JP2010539950A
Publication Date:
January 27, 2011
Filing Date:
November 23, 2009
Export Citation:
Assignee:
Mallinckrodt INC.
International Classes:
C07D491/06; A61K31/5025; A61K41/00; A61P29/00; A61P35/00
Attorney, Agent or Firm:
Takeshi Oshio