Title:
アルファＶインテグリン阻害剤としてのアゾールアミドおよびアミン
Document Type and Number:
Japanese Patent JP7128811
Kind Code:
B2
Abstract:
The present invention provides compounds of Formula (I): (Formula (I)), or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds are inhibitors to αv-containing integrins. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating a disease, disorder, or condition associated with dysregulation of αv-containing integrins, such as pathological fibrosis, transplant rejection, cancer, osteoporosis, and inflammatory disorders, by using the compounds and pharmaceutical compositions.
Inventors:
Pratic de Bastail
WANG,Wei
WANG,Wei
Application Number:
JP2019523847A
Publication Date:
August 31, 2022
Filing Date:
November 07, 2017
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D471/04; A61K31/4375; A61K31/444; A61K31/506; A61P1/16; A61P3/10; A61P9/00; A61P13/12; A61P29/00; A61P37/06; A61P43/00; C07D403/12
Domestic Patent References:
| JP2004511434A | ||||
| JP2007507440A | ||||
| JP2005539049A |
Foreign References:
| WO2011098603A1 |
Attorney, Agent or Firm:
Yamato Kento
Shinagawa
Wu Yingyan
Futami Kamahira
Masahiro Suwon
Shinagawa
Wu Yingyan
Futami Kamahira
Masahiro Suwon