Title:
アゾリジンカーボニトリル類及びそれらのDPP-IV阻害剤としての用途
Document Type and Number:
Japanese Patent JP2007516154
Kind Code:
A
Abstract:
The invention discloses a novel heterocyclic compounds that falls within f the ambit of general formula (I), its stereoisomers, pharmaceutically acceptable salts or solvates wherein X, n,k,z, R1, R2, R3, R4, R5 and R6 are as defined in the specification that are useful in (i) normalizing elevated blood pglucose levels in diabetes, (ii) treating disorders related to glucose intolerance and (iii) for scavenging free radicals of mammals. The invention also discloses pharmaceutically acceptable composition comprising these compounds, method for preparation of the compounds as defined bove and method of treating mammals including human beings by administering an effective amount of said compounds to a subject in need thereof. The invention further discloses use of these compounds in the manufacture of a medicament useful for treatment of different disease conditions as stated above.
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Inventors:
Sankara Narayanan, Arangdi
Application Number:
JP2005509281A
Publication Date:
June 21, 2007
Filing Date:
October 06, 2003
Export Citation:
Assignee:
TORRENT PHARMACEUTICALS LIMITED
International Classes:
C07D263/04; A61K31/454; A61P1/04; A61P1/12; A61P1/16; A61P3/00; A61P3/04; A61P3/10; A61P5/06; A61P5/14; A61P5/16; A61P5/38; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P27/12; A61P29/00; A61P31/18; A61P35/00; A61P39/06; A61P43/00; C07D401/14; C07D417/12; C07D417/14
Attorney, Agent or Firm:
Narumi Morishima
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