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Title:
Babesiacanisワクチン
Document Type and Number:
Japanese Patent JP4446647
Kind Code:
B2
Abstract:
The present invention relates to nucleic acid sequences encoding novel Babesia canis associated proteins and to cDNA fragments, recombinant DNA molecules and live recombinant carriers comprising these sequences. Furthermore, the invention relates to host cells comprising such nucleic acid sequences, cDNA fragments, recombinant DNA molecules and live recombinant carriers. Also, the invention relates to proteins encoded by these nucleotide sequences, to vaccines for combating Babesia canis infections comprising these proteins or genetic material encoding these proteins and methods for the preparation of vaccines. Another embodiment of the invention relates to these Babesia canis associated proteins for use in vaccines and to the use of the Babesia canis associated proteins in the manufacture of vaccines. Finally the invention relates to diagnostic tools for the detection of Babesia canis associated nucleic acid sequences, for the detection of Babesia canis associated antigens and for the detection of antibodies against Babesia canis associated antigenic material.

Inventors:
Theodorus Petrus Maria Schhetsters
Bernard Pierre Dominique Calcy
Pascal Robert Drakiyurovsky
André Francois Golanfro
Application Number:
JP2002042621A
Publication Date:
April 07, 2010
Filing Date:
February 20, 2002
Export Citation:
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Assignee:
Interventional Internal Bee
International Classes:
C12N15/09; A61K39/00; A61K39/018; A61K39/155; A61K39/175; A61K39/205; A61K39/23; A61K39/29; A61K39/39; A61P33/02; C07K14/44; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12Q1/68
Foreign References:
EP1050541A1
EP0691131A1
Other References:
Infection and Immunity,1995年,Vol.63, No.3,pp.811-817
Eur. J. Biochem.,1999年,Vol.265,pp.1015-1021
Attorney, Agent or Firm:
Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura