Title:
細菌のクオラムセンシングの共有結合阻害
Document Type and Number:
Japanese Patent JP5816618
Kind Code:
B2
Abstract:
Inhibitors of bacterial communication, such as quorum sensing, and method of use and manufacture thereof.
Inventors:
Mailer, Michael, M.
Amara, Neri
Layo, Jose
Amara, Neri
Layo, Jose
Application Number:
JP2012516972A
Publication Date:
November 18, 2015
Filing Date:
July 04, 2010
Export Citation:
Assignee:
THE NATIONAL INSTITUTE FOR BIOTECHNOLOGY IN THE NEGEV LTD.
International Classes:
C07D307/33; A01N47/46; A01P3/00; A61K6/02; A61K31/365; A61K45/00; A61L15/58; A61L17/00; A61L24/00; A61L27/00; A61L29/00; A61L31/00; A61P31/04
Domestic Patent References:
| JP2006512290A |
Foreign References:
| WO2001074801A1 | ||||
| WO2003004017A1 |
Other References:
HORIKAWA, MANABU,SYNTHESIS OF PSEUDOMONAS QUORUM-SENSING AUTOINDUCER ANALOGS AND STRUCTURAL ENTITIES 以下備考,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2006年,V16 N8,P2130-2133,REQUIRED FOR INDUCTION OF APOPTOSIS IN MACROPHAGES
SYLVIE REVERCHON, et al.,New synthetic analogues of N-acyl homoserine lactones as agonists or antagonists of transcriptional regulators involved in bacterial quorum sensing,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2002年,Vol.12, No.8 ,pp.1153-1157
SIRI RAM CHHABRA, et al.,Synthetic Analogues of the Bacterial Signal (Quorum Sensing) Molecule N-(3-Oxododecanoyl)-l-homoserine Lactone as Immune Modulators,JOURNAL OF MEDICINAL CHEMISTRY,2003年,Vol.46, No.1,pp.97-104
SPANDL, RICHARD J.,SYNTHESIS OF A BIOTIN-LABELED QUORUM-SENSING MOLECULE: 以下備考,SYNLETT,2008年,V14,P2122-2126,TOWARDS A GENERAL METHOD FOR TARGET IDENTIFICATION
SYLVIE REVERCHON, et al.,New synthetic analogues of N-acyl homoserine lactones as agonists or antagonists of transcriptional regulators involved in bacterial quorum sensing,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2002年,Vol.12, No.8 ,pp.1153-1157
SIRI RAM CHHABRA, et al.,Synthetic Analogues of the Bacterial Signal (Quorum Sensing) Molecule N-(3-Oxododecanoyl)-l-homoserine Lactone as Immune Modulators,JOURNAL OF MEDICINAL CHEMISTRY,2003年,Vol.46, No.1,pp.97-104
SPANDL, RICHARD J.,SYNTHESIS OF A BIOTIN-LABELED QUORUM-SENSING MOLECULE: 以下備考,SYNLETT,2008年,V14,P2122-2126,TOWARDS A GENERAL METHOD FOR TARGET IDENTIFICATION
Attorney, Agent or Firm:
Ryu Iwatani