Title:
行動障害治療剤
Document Type and Number:
Japanese Patent JP4498140
Kind Code:
B2
Abstract:
The present invention provides methods of treating restless legs syndrome or related disorders, comprising administering an effective amount of at least one adenosine A2A receptor antagonist to a patient in need thereof. More preferably the adenosine A2A receptor antagonist is a xanthine derivative or a pharmaceutically acceptable salt thereof.
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Inventors:
Hiroshi Kase
Naoki Senoo
Akihisa Mori
Jao Da Yao
Naoki Senoo
Akihisa Mori
Jao Da Yao
Application Number:
JP2004533000A
Publication Date:
July 07, 2010
Filing Date:
August 27, 2003
Export Citation:
Assignee:
Kyowa Hakko Kirin Co., Ltd.
International Classes:
A61K31/522; C07D473/06; A61K31/00; A61K45/00; A61P1/14; A61P1/16; A61P3/02; A61P3/10; A61P3/12; A61P5/14; A61P7/02; A61P7/06; A61P7/08; A61P11/00; A61P11/16; A61P13/02; A61P15/00; A61P19/02; A61P25/00; A61P25/02; A61P25/08; A61P25/14; A61P25/20; A61P25/28; A61P25/32; A61P29/00; A61P35/00; A61P43/00
Foreign References:
| WO2001062290A1 |
Other References:
Annals of Neurology,1998年,Vol.43,P.507-513
ALLEN,R.P. et al,Restless legs syndrome: a review of clinical and pathophysiologic features,J Clin Neurophysiol,2001年,Vol.18, No.2,p.128-47
ONDO,W.G. et al,Exploring the relationship between Parkinson disease and restless legs syndrome,Arch Neurol,2002年 3月,Vol.59, No.3,p.421-4
ASKENASY,J.J.,Approaching disturbed sleep in late Parkinson's Disease: first step toward a proposal for a revised UPDRS,Parkinsonism Relat Disord,2001年,Vol.8, No.2,p.123-31
ALLEN,R.P. et al,Restless legs syndrome: a review of clinical and pathophysiologic features,J Clin Neurophysiol,2001年,Vol.18, No.2,p.128-47
ONDO,W.G. et al,Exploring the relationship between Parkinson disease and restless legs syndrome,Arch Neurol,2002年 3月,Vol.59, No.3,p.421-4
ASKENASY,J.J.,Approaching disturbed sleep in late Parkinson's Disease: first step toward a proposal for a revised UPDRS,Parkinsonism Relat Disord,2001年,Vol.8, No.2,p.123-31