Title:
Benzamides
Document Type and Number:
Japanese Patent JP6162694
Kind Code:
B2
Abstract:
Novel benzamide derivatives of formula (I)
wherein W 1 , W 2 , R 1 to R 7 , R 6 , X and Y have the meaning according to the claims, are positive allosteric modulators of the FSH receptor, and can be employed, inter alia, for the treatment of fertility disorders.
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Inventors:
Henry Yu
Richetchen
Thomas E. Richardson
Pandy balati
Brian H. Heasley
Andreas Goat Poulos
Richetchen
Thomas E. Richardson
Pandy balati
Brian H. Heasley
Andreas Goat Poulos
Application Number:
JP2014521705A
Publication Date:
July 12, 2017
Filing Date:
July 17, 2012
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D207/34; A61K31/496; A61K31/506; A61K31/5377; A61K31/706; A61P15/08; A61P43/00; C07D263/34; C07D263/38; C07D277/56; C07D307/68; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07D413/12; C07D417/12; C07H5/06
Domestic Patent References:
| JP2011512412A | ||||
| JP2010520228A | ||||
| JP2009532407A | ||||
| JP2008543898A | ||||
| JP2003516978A | ||||
| JP2002506458A | ||||
| JP9059236A | ||||
| JP2002539207A | ||||
| JP7258224A | ||||
| JP2007512294A | ||||
| JP2006519214A | ||||
| JP2006505568A | ||||
| JP2004528334A |
Foreign References:
| WO2007002742A1 | ||||
| WO1999020606A1 | ||||
| WO2008123469A1 | ||||
| WO2005108370A1 | ||||
| WO1997029079A1 | ||||
| WO2010034796A1 | ||||
| WO2007133983A1 |
Other References:
COLE ANDREW G.,IDENTIFICATION AND INITIAL EVALUATION OF 4-N-ARYL-[1,4]DIAZEPANE UREAS AS POTENT CXCR3 ANTAGONISTS,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,英国,PERGAMON, ELSEVIER SCIENCE,2006年 1月 1日,V16 N1,P200-203
BEG M. S. J.,SYNTHESIS OF 1-(N-SUBSTITUTED-CARBOXAMIDO-2-AMINOPHENYL)-4-METHYL-PIPERAZINES: 以下備考,ASIAN JOURNAL OF CHEMISTRY,IN,CHEMIC PUBLISHING,2003年 1月 1日,V15 N3-4,P1343-1346,D.E.C. ANALOGS AND THEIR ANTIFILARIAL ACTIVITY-II
NEFZI ADEL,DIVERSITY-ORIENTED SYNTHESIS OF N-ARYL-N-THIAZOLYL COMPOUNDS,TETRAHEDRON LETTERS,NL,ELSEVIER,2010年 9月15日,V51 N37,P4797-4800
Begunov, R. S. et al,Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya I Khimicheskaya Tekhnologiya,2005年,vol.48 no.11,p.56-57
Bieksa, V. et al,Lietuvos TSR Mokslu Akademijos Darbai, Serija B: Chemija, Technika, Fizine Geografija,1971年,vol.1,p.133-143
REGISTRY(STN)[online],2002.10.11[検索日 2016.02.18]CAS登録番号 460735-77-7
Siddappa, C. et al,Tetrahedrn Letters,2010年,vol.51,p.6493-6497
South, M. S. et al,Combinatorial Chemistry & High Throughput Screening,2000年,vol.3,p.139-151
BEG M. S. J.,SYNTHESIS OF 1-(N-SUBSTITUTED-CARBOXAMIDO-2-AMINOPHENYL)-4-METHYL-PIPERAZINES: 以下備考,ASIAN JOURNAL OF CHEMISTRY,IN,CHEMIC PUBLISHING,2003年 1月 1日,V15 N3-4,P1343-1346,D.E.C. ANALOGS AND THEIR ANTIFILARIAL ACTIVITY-II
NEFZI ADEL,DIVERSITY-ORIENTED SYNTHESIS OF N-ARYL-N-THIAZOLYL COMPOUNDS,TETRAHEDRON LETTERS,NL,ELSEVIER,2010年 9月15日,V51 N37,P4797-4800
Begunov, R. S. et al,Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya I Khimicheskaya Tekhnologiya,2005年,vol.48 no.11,p.56-57
Bieksa, V. et al,Lietuvos TSR Mokslu Akademijos Darbai, Serija B: Chemija, Technika, Fizine Geografija,1971年,vol.1,p.133-143
REGISTRY(STN)[online],2002.10.11[検索日 2016.02.18]CAS登録番号 460735-77-7
Siddappa, C. et al,Tetrahedrn Letters,2010年,vol.51,p.6493-6497
South, M. S. et al,Combinatorial Chemistry & High Throughput Screening,2000年,vol.3,p.139-151
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Tatsunori Ikeda
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Masaru Nakajima
Tatsunori Ikeda
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