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Title:
ベンザゼピンジカルボキサミド化合物
Document Type and Number:
Japanese Patent JP6728208
Kind Code:
B2
Abstract:
wherein R1 to R4 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are TLR agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases.

Inventors:
Hove's, Sabine
Wan, Leisher
Yun, Hong Yin
Chan, Weishin
Chu, Way
Application Number:
JP2017546806A
Publication Date:
July 22, 2020
Filing Date:
March 03, 2016
Export Citation:
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Assignee:
Ef Hoffman-La Roche Akchengezel Shaft
International Classes:
C07D223/16; A61K31/55; A61P11/06; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D401/12; C07D403/12; C07D413/12; C07D417/12
Domestic Patent References:
JP2009504763A
JP2013538860A
JP2013502431A
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation