BENZENE DERIVATIVE, MANUFACTURE AND MEDICINAL COMPOSITION

Title:

BENZENE DERIVATIVE, MANUFACTURE AND MEDICINAL COMPOSITION

Document Type and Number:

Japanese Patent JPS5916872

Kind Code:

A

Abstract:

1-amino-4-oxy-3-(mercapto-alkyl)-(unbranched chain)-benzenes, having particularly the formula (I) wherein R and R2 are hydrogen or an alkyl residue with 1 to 6 atoms of carbon, R' is hydrogen, an alkyl residue with 1 to 6 atoms of carbon or the group -COR1 wherein R1 is hydrogen or an alkyl residue with 1 to 6 atoms of carbon, and A is an unbranched alkyl chain with 5 atoms of carbon at the most, as well as their S-acylated derivatives, S-S-dimers derivatives and salts thereof. Those compounds have a pharmacological activity, particularly an analgesic activity.

Inventors:

ROORANTO ACHIINI
RASHIYURO REBESHIYU

Application Number:

JP10909983A

Publication Date:

January 28, 1984

Filing Date:

June 16, 1983

Export Citation:

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Assignee:

SANDOZ AG

International Classes:

A61K31/16; A61K31/165; A61K31/265; A61P25/04; A61P29/00; C07C67/00; C07C313/00; C07C323/29; C07C325/00; A61K31/135; C07C327/30; C07C329/06; C07C335/32; C07D277/14; (IPC1-7): A61K31/135; A61K31/16; A61K31/265; A61K31/425; C07C149/42; C07C153/07; C07C154/02; C07C157/14; C07D277/14

Attorney, Agent or Firm:

Aoyama

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