Title:
レチノイド関連オーファン受容体ガンマ（ＲＯＲガンマ（ｔ））のインバースアゴニストとしてのベンゼンスルホンアミド誘導体
Document Type and Number:
Japanese Patent JP6683709
Kind Code:
B2
Abstract:
Benzenesulfonamide derivatives of formula (I), the pharmaceutically acceptable addition salts thereof, the hydrates and/or solvates thereof, and the use of same as inverse agonist of retinoid-related orphan receptor gamma (RORγt) are described. A pharmaceutical composition including such compounds, as well as the use thereof for the topical and/or oral treatment of RORγt receptor-medicated inflammatory diseases, in particular acne, psoriasis and/or atopic dermatitis are also described.
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Inventors:
Branislav Musikki
Jill Woobury
Etienne Thoreau
Claire Buoy-Peter
Jill Woobury
Etienne Thoreau
Claire Buoy-Peter
Application Number:
JP2017533268A
Publication Date:
April 22, 2020
Filing Date:
December 18, 2015
Export Citation:
Assignee:
Galderma Research and Development
International Classes:
C07D211/22; A61K31/18; A61K31/337; A61K31/343; A61K31/351; A61K31/381; A61K31/382; A61K31/42; A61K31/4409; A61K31/445; A61K31/5415; A61P3/02; A61P17/04; A61P17/06; A61P17/10; A61P29/00; A61P37/06; A61P37/08; A61P43/00; C07D211/26; C07D211/46; C07D211/96; C07D213/30; C07D261/08; C07D279/16; C07D305/06; C07D305/08; C07D307/77; C07D309/04; C07D309/06; C07D309/08; C07D333/48; C07D335/02; C07D417/06
Domestic Patent References:
| JP2014519855A | ||||
| JP2010530396A | ||||
| JP2017511357A | ||||
| JP2008546636A |
Foreign References:
| WO2014090712A1 | ||||
| WO2013160418A1 | ||||
| WO2015145371A1 | ||||
| WO2012139775A1 |
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe