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Title:
BENZOOXAZOLE DERIVATIVE
Document Type and Number:
Japanese Patent JPH10158116
Kind Code:
A
Abstract:

To obtain a new benzooxazole derivative useful as a sun screen agent in cosmetic compositions and as a photostabilizer for protecting synthetic polymers.

A compound of formula I {R, R1 are each H, a 1-8C alkyl, OR5 (R5 is a 1-4C alkyl), COOR6 (R6 is a 1-24C alkyl, a 7-12C aralkyl, a 5-8C cycloalkyl, a group of formula II [A is a 1-8C alkyl, a 6-10C aryl, etc.; R7 is H, methyl; (n) is 1-10], etc.; R2 is a group of formula III (R9, R10 are each R), etc.; R3 is an alkyl, a group of formula III, etc.; R4 is H, an alkyl; R3 and R4 form a five to seven-membered heterocyclic ring together with N}, e.g. 2-(p- aminophenyl)benzooxazole. The compound of formula I is obtained by reacting a compound of formula IV (Z is preferably Br, Cl) with a compound of the formula: R2-NH2. The compound of formula I exhibits excellent compatibility with components usually used in cosmetics.


Inventors:
RASPANTI GIUSEPPE
ZANCHI GIORGIO
Application Number:
JP24653497A
Publication Date:
June 16, 1998
Filing Date:
September 11, 1997
Export Citation:
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Assignee:
3V SIGMA SPA
International Classes:
C07D263/56; A61K8/19; A61K8/30; A61K8/33; A61K8/35; A61K8/37; A61K8/41; A61K8/46; A61K8/49; A61K31/53; A61P17/00; A61Q1/00; A61Q1/02; A61Q1/04; A61Q1/06; A61Q17/04; A61Q19/00; C07D413/12; C07D413/14; C08K5/3492; C08K5/353; (IPC1-7): A61K7/00; A61K7/02; A61K31/53; C07D413/12; C08K5/3492
Attorney, Agent or Firm:
Wakabayashi Tadashi