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Title:
BICYCLIC PIPERAZINE COMPOUND AND ITS USE
Document Type and Number:
Japanese Patent JP2005306839
Kind Code:
A
Abstract:

To obtain a compound which has a TGR23 (G protein conjugated type receptor) antagonist activity and is useful for preventing and treating cancer.

The compound represented by the formula (wherein R1 is an acyl group; R2, R3, and R4 are each an optionally substituted hydrocarbon group, or the like; (n) is 0-4; and X is O or S) or its salt is provided.


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Inventors:
FUKATSU KOJI
NAKAYAMA YUTAKA
TARUI NAOKI
MORI MASAAKI
MATSUMOTO HIROKAZU
KURASAWA OSAMU
SAKANO HIROSHI
Application Number:
JP2004247166A
Publication Date:
November 04, 2005
Filing Date:
August 26, 2004
Export Citation:
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Assignee:
TAKEDA CHEMICAL INDUSTRIES LTD
International Classes:
C07D498/04; A61K31/4985; A61K31/5377; A61K31/541; A61K31/55; A61P3/06; A61P3/10; A61P5/06; A61P5/14; A61P5/24; A61P9/12; A61P25/18; A61P25/28; A61P35/00; A61P43/00; (IPC1-7): C07D498/04; A61K31/4985; A61K31/5377; A61K31/541; A61K31/55; A61P3/06; A61P3/10; A61P5/06; A61P5/14; A61P5/24; A61P9/12; A61P25/18; A61P25/28; A61P35/00; A61P43/00
Domestic Patent References:
JP2000072771A2000-03-07
JP2000516639A2000-12-12
Foreign References:
WO2002018327A22002-03-07
WO2003030907A12003-04-17
WO2002000631A22002-01-03
WO2003053354A22003-07-03
WO2002018372A12002-03-07
WO2001089570A22001-11-29
WO2003020699A22003-03-13
WO2003011824A12003-02-13
WO2002000654A12002-01-03
Attorney, Agent or Firm:
Takashima Ichi



 
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