Title:
抗腫瘍および抗神経変性剤としての二環式ピラゾールおよびイソオキサゾール誘導体
Document Type and Number:
Japanese Patent JP5063815
Kind Code:
B2
Abstract:
Bicyclic pyrazole and isoxazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases mediated by HSP90 protein, like cancer and neurodegenerative disorders.
Inventors:
Mantegani, Sergio
Blasca, Maria Gabriella
Cassie Tsuri, Franchiesco
Farugasson, Ron
Posta, Elena
Carlo, Bisco
Casale, Elena
Zukkotto, Huavio
Blasca, Maria Gabriella
Cassie Tsuri, Franchiesco
Farugasson, Ron
Posta, Elena
Carlo, Bisco
Casale, Elena
Zukkotto, Huavio
Application Number:
JP2011536866A
Publication Date:
October 31, 2012
Filing Date:
November 19, 2009
Export Citation:
Assignee:
Nerbiano Medieval Sciences Etse Erle Erle
International Classes:
C07D471/04; A61K31/4162; A61K31/437; A61K31/444; A61K31/4545; A61K31/496; A61K31/5377; A61K31/541; A61K45/00; A61P21/00; A61P25/00; A61P25/14; A61P25/16; A61P25/28; A61P35/00; A61P35/02; A61P43/00; C07D487/04; C07D498/04
Foreign References:
| WO2004050087A1 | ||||
| WO2008104595A1 | ||||
| WO2003101989A1 | ||||
| WO2007131153A1 | ||||
| WO2005040169A1 |
Attorney, Agent or Firm:
Kawaguchi International Patent Office