Title:
BILE ACID 11-HYDROXYL DERIVATIVES AND AMINO ACID CONJUGATES THEREOF, AS FARNESOID X RECEPTOR MODULATORS
Document Type and Number:
Japanese Patent JP2018127481
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide bile acid 11-hydroxyl derivatives and amino acid conjugates thereof, as farnesoid X receptor modulators.SOLUTION: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. [In the formula, Ris hydroxyl; Ris hydrogen, hydroxyl, alkyl, or halogen; Ris hydrogen, hydroxyl, alkyl, or halogen; and R4 is hydrogen, alkyl, alkenyl, alkynyl, or halogen.]SELECTED DRAWING: None
Inventors:
ROBERTO PELLICCIARI
Application Number:
JP2018077654A
Publication Date:
August 16, 2018
Filing Date:
April 13, 2018
Export Citation:
Assignee:
INTERCEPT PHARMACEUTICALS INC
International Classes:
C07J9/00; A61K31/575; A61P1/04; A61P1/16; A61P3/00; A61P3/06; A61P3/10; A61P9/00; A61P9/10; A61P13/12; A61P23/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
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