Title:
ナノ粒子医薬組成物に有用な生体適合性、非生物分解性、非毒性ポリマー
Document Type and Number:
Japanese Patent JP2009522251
Kind Code:
A
Abstract:
The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidone (VP), N-Isopropylacrylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds.
Inventors:
Anand Sea Berman
Rama Mukherjee
Dirage Cutter
Sanjoy Murick
Manu Juggi
Manoi Kumar Singh
Mukesh Kumar
Deepak Plasticy
Pawan Kumar Gupta
Rajendran Plavin
Shob hit shin
Rama Mukherjee
Dirage Cutter
Sanjoy Murick
Manu Juggi
Manoi Kumar Singh
Mukesh Kumar
Deepak Plasticy
Pawan Kumar Gupta
Rajendran Plavin
Shob hit shin
Application Number:
JP2008548083A
Publication Date:
June 11, 2009
Filing Date:
December 26, 2006
Export Citation:
Assignee:
Dabul Pharma Limited
International Classes:
A61K47/34; A61K9/51; A61K31/05; A61K31/19; A61K31/192; A61K31/337; A61K31/7048; A61K47/02; A61K47/10; A61K47/12; A61K47/18; A61K47/20; A61K47/26; A61K47/28; A61K47/32; A61K47/36; C08F290/06
Foreign References:
| US6322817B1 | 2001-11-27 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Masahiro Nitta
Samejima Mutsumi
Masahiro Nitta
Previous Patent: 再生可能資源由来の官能基化ドーパント／導電性ポリアミン材料、混合物...
Next Patent: カルボキシエチルホスフィネートエステルの塩、及びこれを含む難燃性熱...
Next Patent: カルボキシエチルホスフィネートエステルの塩、及びこれを含む難燃性熱...