Title:
抗炎症活性を有するビス-(クマリン)化合物
Document Type and Number:
Japanese Patent JP2008526951
Kind Code:
A
Abstract:
Certain bis-(coumarin) compounds as well as the products of their intramolecular cyclization including pharmaceutically acceptable salts, hydrates, solvates, clathrates, prodrugs, tautomers and stereoisomers thereof are disclosed. Certain processes and intermediates for the preparation of certain bis-(coumarin) compounds, as well as for the use of these compounds as therapeutically active agents in the prophylaxis and treatment of asthma and other inflammatory diseases and conditions in mammals, especially humans are also disclosed.
Inventors:
Muraden Mercep
Ivika Marnar
Bosca Fullvatic
Stribol Markovic
Anita Filipovic Stick
Belislav Bosniak
Andreya Cempow Kronkai
Renata Ruptic
Antun Futineck
Ibiro Ivkov Erenkov
Milan Mesic
Ivika Marnar
Bosca Fullvatic
Stribol Markovic
Anita Filipovic Stick
Belislav Bosniak
Andreya Cempow Kronkai
Renata Ruptic
Antun Futineck
Ibiro Ivkov Erenkov
Milan Mesic
Application Number:
JP2007550880A
Publication Date:
July 24, 2008
Filing Date:
January 13, 2006
Export Citation:
Assignee:
GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O.
International Classes:
C07D311/56; A61K31/37; A61K31/381; A61K31/4178; A61K31/4433; A61K31/4709; A61P1/00; A61P9/00; A61P9/10; A61P11/06; A61P13/12; A61P17/02; A61P19/02; A61P25/00; A61P25/04; A61P25/28; A61P27/02; A61P29/00; A61P37/08; C07D311/44; C07D405/14; C07D407/14; C07D409/14; C07D493/04; C07D493/14
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita