Title:
骨・関節疾患感受性遺伝子およびその用途
Document Type and Number:
Japanese Patent JP5076058
Kind Code:
B2
Abstract:
The present invention provides the prophylaxis and treatment of bone and joint diseases by regulating the expression or activity of calmodulin, the prophylaxis and treatment of bone and joint diseases by regulating the expression or activity of asporin, and a diagnostic method for genetic susceptibility to bone and joint diseases by detecting polymorphisms in the CALM1 gene and/or the asporin gene, and the like.
Inventors:
Shiro Ikegawa
Hideki Kizawa
Hideyuki Motoya
Hideki Kizawa
Hideyuki Motoya
Application Number:
JP2006531667A
Publication Date:
November 21, 2012
Filing Date:
August 03, 2005
Export Citation:
Assignee:
RIKEN
Shiro Ikegawa
Takeda GmbH
Shiro Ikegawa
Takeda GmbH
International Classes:
C12N15/09; A61K38/00; A61K39/395; A61P19/00; A61P19/02; A61P19/10; A61P29/00; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53
Foreign References:
| WO2003061565A2 | 2003-07-31 | |||
| US5698518A | 1997-12-16 |
Attorney, Agent or Firm:
Takashima Ichi