Title:
ブタン酸誘導体、その調製方法、それらを含む医薬組成物およびその治療用途
Document Type and Number:
Japanese Patent JP5295560
Kind Code:
B2
Abstract:
Compounds of the formula (I): in which R, R1 and R2 are as defined in the description, the use thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, pharmaceutical compositions comprising them, and . processes for the preparation of these compounds. Compounds of formula (I) are activators of PPARα and PPARα isoforms.
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Inventors:
Zeille, Jean Jean
Dumas, Herve
Guyard-Dangmon, Valerie
Belar, isabelle
Contar, Francis
Greer, Daniel
Ferrand, Gerard
Monom, Eve
Dumas, Herve
Guyard-Dangmon, Valerie
Belar, isabelle
Contar, Francis
Greer, Daniel
Ferrand, Gerard
Monom, Eve
Application Number:
JP2007511903A
Publication Date:
September 18, 2013
Filing Date:
April 06, 2005
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D277/24; A61K31/15; A61K31/192; A61K31/216; A61K31/235; A61K31/277; A61K31/34; A61K31/341; A61K31/36; A61K31/381; A61K31/39; A61K31/415; A61K31/4196; A61K31/42; A61K31/423; A61K31/426; A61K31/428; A61K31/433; A61K31/4375; A61K31/4406; A61K31/47; A61K31/472; A61K31/498; A61K31/513; A61K31/535; A61K31/538; A61P3/06; A61P3/10; A61P9/10; C07C51/09; C07C59/13; C07C59/205; C07C59/68; C07C67/313; C07C69/712; C07C69/734; C07C69/738; C07C69/92; C07C201/12; C07C205/37; C07C205/45; C07C205/60; C07C213/08; C07C217/86; C07C249/12; C07C251/58; C07C253/30; C07C255/54; C07C255/57; C07C315/04; C07C317/14; C07C317/22; C07C319/20; C07C323/20; C07D213/30; C07D213/50; C07D213/64; C07D213/65; C07D213/76; C07D213/89; C07D215/14; C07D215/20; C07D215/26; C07D217/02; C07D231/06; C07D231/12; C07D231/28; C07D239/52; C07D239/54; C07D241/44; C07D249/08; C07D261/08; C07D263/56; C07D263/57; C07D265/38; C07D277/10; C07D277/66; C07D285/06; C07D295/08; C07D295/096; C07D307/42; C07D307/46; C07D307/60; C07D307/79; C07D307/80; C07D307/82; C07D307/86; C07D307/91; C07D311/14; C07D311/16; C07D311/18; C07D311/22; C07D311/24; C07D311/30; C07D311/54; C07D311/56; C07D311/58; C07D311/74; C07D311/76; C07D317/64; C07D327/04; C07D333/16; C07D333/22; C07D333/28; C07D333/56; C07D409/04; C07D471/04; C07D471/06; C07B53/00; C07B61/00
Domestic Patent References:
| JP2001261612A | ||||
| JP2085262A | ||||
| JP64000550A |
Foreign References:
| US3378582 | ||||
| WO2003002575A1 | ||||
| WO2002100398A1 |
Attorney, Agent or Firm:
Akio Miyazaki
Ishibashi Masayuki
Masaaki Ogata
Ishibashi Masayuki
Masaaki Ogata