Title:
C-17 and C-3 ornamentation triterpenoid which have HIV mature prevention activity
Document Type and Number:
Japanese Patent JP6001560
Kind Code:
B2
Abstract:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 and C-3 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.
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| WO/2017/021922 | NOVEL SUBSTITUTED AMIDES OF TRITERPENE DERIVATIVES AS HIV INHIBITORS |
Inventors:
Alicia Regueiro-Len
Chen Liu
Jacob Swidoski
Nai Singh
Brian Lee Bennables
Shin-Yuen Sitt
Yang Chen
Chen Jie
Nicholas A. Meanwell
Chen Liu
Jacob Swidoski
Nai Singh
Brian Lee Bennables
Shin-Yuen Sitt
Yang Chen
Chen Jie
Nicholas A. Meanwell
Application Number:
JP2013551362A
Publication Date:
October 05, 2016
Filing Date:
January 27, 2012
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07J63/00; A61K31/56; A61K31/7024; A61K45/00; A61P31/12; A61P31/18
Foreign References:
| WO2009100532A1 | ||||
| WO2011153315A1 | ||||
| WO2011153319A1 |
Attorney, Agent or Firm:
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Nagatoshi Shinagawa
Yasushi Morimoto