Title:
IGFR経路のモディファイヤーとしてのC20ORF23及び使用方法
Document Type and Number:
Japanese Patent JP2007528735
Kind Code:
A
Abstract:
Human C20ORF23 genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of C20ORF23 are provided.
Inventors:
Friedman, Lori
Francis-Lung, Helen
Parkes, Annette L.
Show, kenneth james
Beerk, Lin Margaret
Hugh, Timothy S.
Francis-Lung, Helen
Parkes, Annette L.
Show, kenneth james
Beerk, Lin Margaret
Hugh, Timothy S.
Application Number:
JP2007503045A
Publication Date:
October 18, 2007
Filing Date:
March 10, 2005
Export Citation:
Assignee:
Excelixis, Inc.
International Classes:
C12Q1/68; A61K38/00; C07K1/00; C12N15/00; C12Q1/02; C12Q1/42; C12Q1/44; G01N33/15; G01N33/50; G01N33/53; G01N33/536; G01N33/566; G01N33/574; G01N33/74; C12N15/09
Foreign References:
| WO2004065545A2 | 2004-08-05 | |||
| WO2004065545A2 | 2004-08-05 |
Other References:
JPN6010071240, Ｒｅｃｅｎｔ ｐｒｏｇｒｅｓｓ ｉｎ ｈｏｒｍｏｎｅ ｒｅｓｅａｒｃｈ． ２００３， Ｖｏｌ．５８， ｐ．３２５−３４２
JPN6010071241, Ｈｏｍｏ ｓａｐｉｅｎｓ ｃｈｒｏｍｏｓｏｍｅ ２０ ｏｐｅｎ ｒｅａｄｉｎｇ ｆｒａｍｅ ２３ （Ｃ２０ｏｒｆ２３）， ｍＲＮＡ． ［ｏｎｌｉｎｅ］． ２６−ＪＡＮ−２００４． ＮＣＢＩ Ｅｎｔｒｅ
JPN6010071241, Ｈｏｍｏ ｓａｐｉｅｎｓ ｃｈｒｏｍｏｓｏｍｅ ２０ ｏｐｅｎ ｒｅａｄｉｎｇ ｆｒａｍｅ ２３ （Ｃ２０ｏｒｆ２３）， ｍＲＮＡ． ［ｏｎｌｉｎｅ］． ２６−ＪＡＮ−２００４． ＮＣＢＩ Ｅｎｔｒｅ
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori