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Title:
A C4-monomethyl triterpenoid derivative and directions for use for the same
Document Type and Number:
Japanese Patent JP6129084
Kind Code:
B2
Abstract:
Disclosed herein are novel C4-monomethyl triterpenoid compounds and derivatives thereof, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds, for example as antioxidant inflammation modulators, and compositions thereof are also provided.

Inventors:
Anderson Eric
Jiang Shin
Bisnick merlin
Bender Christopher F.
Ryu Xiao Fong
Application Number:
JP2013557919A
Publication Date:
May 17, 2017
Filing Date:
March 09, 2012
Export Citation:
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Assignee:
Riata Pharmaceuticals, Inc.
International Classes:
C07J63/00; A61K31/277; A61K31/337; A61K31/357; A61K31/397; A61K31/40; A61K31/4164; A61K31/4245; A61K31/445; A61K31/5377; A61P1/04; A61P1/18; A61P3/10; A61P9/10; A61P11/00; A61P13/12; A61P17/06; A61P21/02; A61P21/04; A61P25/00; A61P25/04; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P35/00; A61P37/06; A61P37/08; C07J71/00
Foreign References:
WO2009129545A1
Other References:
TADASHI HONDA ET AL,THE JOURNAL OF ORGANIC CHEMISTRY,1998年,VOL.63, NO.14,PP.4846-4849
RUZICKA L. ET AL,HELVETICA CHIMICA ACTA,1944年,VOL.27,PP.1185-1196
TADASHI HONDA ET AL.,J. MED. CHEM.,2000年,VOL.43, NO.9,PP.1866-1877
CHEUNG. H. T. ET AL,PHYTOCHEMISTRY,1972年,VOL.11,PP.1771-1780
JOHNS, S. R. ET AL,AUSTR. J. CHEM.,1983年,VOL.36,PP.2537-2547
PEAKMAN, T. M., ET AL,TETRAHEDRON,1991年,VOL.47, NO.23,PP.3779-3786
WOLFF, G. A. ET AL,TETRAHEDRON,1989年,VOL.45, NO.21,PP.6721-6728
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto