Title:
CCR9インヒビターおよびその使用方法
Document Type and Number:
Japanese Patent JP4818798
Kind Code:
B2
Abstract:
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
Inventors:
Paul Fleming
Geraldine C. B. Harriman
Zanshi
Chen Xiaou
Geraldine C. B. Harriman
Zanshi
Chen Xiaou
Application Number:
JP2006124437A
Publication Date:
November 16, 2011
Filing Date:
April 27, 2006
Export Citation:
Assignee:
MILLENNIUM PHARMACEUTICALS, INC.
International Classes:
C07D333/34; A61K31/18; A61K31/381; A61K31/44; A61K31/4409; A61K31/4425; A61K31/444; A61P1/04; A61P3/10; A61P5/14; A61P9/00; A61P9/10; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/28; A61P29/00; A61P37/06; A61P37/08; A61P43/00; C07C311/21; C07C311/29; C07C311/44; C07C311/46; C07C317/34; C07C321/30; C07C323/49; C07D213/30; C07D213/50; C07D213/65; C07D213/70; C07D213/71; C07D213/75; C07D213/76; C07D213/80; C07D213/89; C07D237/08; C07D239/26; C07D239/42; C07D333/62; C07D405/06; C07D409/04; C07D409/06; C07D413/04; C07D413/14; C07D513/04; A61K31/63
Domestic Patent References:
| JP6135934A | ||||
| JP5092956A | ||||
| JP2003508388A | ||||
| JP2003522189A | ||||
| JP2003523998A | ||||
| JP2003533510A |
Foreign References:
| US3402171 | ||||
| GB884847B |
Other References:
European Journal of Medicinal Chemistry,2002年,37(2),p.147-161
Tetrahedron,2001年,57(27),p.5885-5895
Bollettino Chimico Farmaceutico,1995年,134(2),p.81-84
Heterocycles,1985年,23(10),p.2651-2661
Tetrahedron,2001年,57(27),p.5885-5895
Bollettino Chimico Farmaceutico,1995年,134(2),p.81-84
Heterocycles,1985年,23(10),p.2651-2661
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita