Title:
ＣＤ３８抗体
Document Type and Number:
Japanese Patent JP7299873
Kind Code:
B2
Abstract:
The present disclosure provides antibody sequences found in antibodies that bind to human CD38. In particular, the present disclosure provides sequences of anti-human CD38 antibodies. Antibodies and antigen-binding portions thereof including such sequences present features compatible with pharmaceutical manufacturing and development can be provided as fully human antibodies (e.g., fully human monoclonal antibodies or antigen-binding fragments) that can be useful for medical methods and compositions, in particular for treating cancer.
Inventors:
Gouvier Anne
Salim Josephine
goyentea corso beatriz
Melhiels Pascal
moulder kevin
Eisler Nina
Philost Simone
Balua Hemanta
Prinz Bianca
Salim Josephine
goyentea corso beatriz
Melhiels Pascal
moulder kevin
Eisler Nina
Philost Simone
Balua Hemanta
Prinz Bianca
Application Number:
JP2020508320A
Publication Date:
June 28, 2023
Filing Date:
August 16, 2018
Export Citation:
Assignee:
Black Belt Therapeutics Limited
International Classes:
C12N15/13; A61K39/395; A61K45/00; A61P35/00; A61P43/00; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/63; C12P21/08
Domestic Patent References:
| JP2010506582A |
Other References:
DECKERT, J. et al.,SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies,Clinical cancer research,2014年,20,4574-4583
FENG, X. et al.,Targeting CD38 Suppresses Induction and Function of T Regulatory Cells to Mitigate Immunosuppression in Multiple Myeloma.,Clinical cancer research,2017年03月,23,4290-4300
FENG, X. et al.,Targeting CD38 Suppresses Induction and Function of T Regulatory Cells to Mitigate Immunosuppression in Multiple Myeloma.,Clinical cancer research,2017年03月,23,4290-4300
Attorney, Agent or Firm:
Saegusa International Patent Office
Previous Patent: Dry polymer application method
Next Patent: OPTICAL MOLDING DEVICE USING HIGH NA OPTICAL SYSTEM
Next Patent: OPTICAL MOLDING DEVICE USING HIGH NA OPTICAL SYSTEM