Title:
前立腺癌におけるホルモンエスケープのマーカーとしてのCXCL5
Document Type and Number:
Japanese Patent JP2013533458
Kind Code:
A
Abstract:
The invention relates to the use of CXCL5 as a marker for assessing hormone escape in prostate cancer cells. The invention further provides diagnostic methods and kits for assessing hormone escape in prostate cancer cells, and CXCL5 antagonists for use in the treatment or prevention of prostate cancer and/or hormone escape in prostate cancer.
Inventors:
Lazeneck, Gwendal
Vendreux, David
Madrid, Bridget
Vendreux, David
Madrid, Bridget
Application Number:
JP2013505450A
Publication Date:
August 22, 2013
Filing Date:
April 19, 2011
Export Citation:
Assignee:
Institut National De La Sante & De La Recherche Medical
International Classes:
G01N33/53; A01K67/027; A61K31/7105; A61K38/00; A61K45/00; A61K48/00; A61P13/08; A61P35/00; C07K16/00; C12Q1/68; G01N33/15; G01N33/50; G01N33/543; C12N15/09
Other References:
JPN7014002251; Ｈ． Ｍｉｙａｚａｋｉ ｅｔ ａｌ．: 'Ｄｏｗｎ-ｒｅｇｕｌａｔｉｏｎ ｏｆ ＣＸＣＬ５ Ｉｎｈｉｂｉｔｓ Ｓｑｕａｍｏｕｓ Ｃａｒｃｉｎｏｇｅｎｅｓｉｓ' Ｃａｎｃｅｒ Ｒｅｓ ２００６； ６６： （８）． Ａｐｒｉｌ １５， ２００６ Ｖｏｌ． ６６， Ｎｏ． ８, 20060415, ｐｐ． ４２７９-４２８４
JPN7014002252; Ｌ． Ａ． Ｂｅｇｌｅｙ ｅｔ ａｌ．: 'ＣＸＣＬ５ Ｐｒｏｍｏｔｅｓ Ｐｒｏｓｔａｔｅ Ｃａｎｃｅｒ Ｐｒｏｇｒｅｓｓｉｏｎ' Ｎｅｏｐｌａｓｉａ Ｖｏｌ． １０， Ｎｏ． ３, 2008, ｐｐ． ２４４-２５４
JPN7014002252; Ｌ． Ａ． Ｂｅｇｌｅｙ ｅｔ ａｌ．: 'ＣＸＣＬ５ Ｐｒｏｍｏｔｅｓ Ｐｒｏｓｔａｔｅ Ｃａｎｃｅｒ Ｐｒｏｇｒｅｓｓｉｏｎ' Ｎｅｏｐｌａｓｉａ Ｖｏｌ． １０， Ｎｏ． ３, 2008, ｐｐ． ２４４-２５４
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Akio Shibata
Yuichi Okazaki
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Akio Shibata
Yuichi Okazaki