Title:
カンプトテシン‐カルボキシレート配合物
Document Type and Number:
Japanese Patent JP2005535633
Kind Code:
A
Abstract:
A composition comprising the carboxylate form of a camptothecin drug or a derivative thereof associated with at least one organic cationic molecule which has a positive net charge cationic molecule), wherein said composition has a molar ratio of at least about 1:1 of an organic cationic molecule to camptothecin carboxylate and is substantially free of the lactone form of said drug or a derivative thereof.
Inventors:
Heinrich Haas
Brita Schulze
Uwe Michaelis
Michael Taifel
Birgitta Sauer
Thomas fichert
Brita Schulze
Uwe Michaelis
Michael Taifel
Birgitta Sauer
Thomas fichert
Application Number:
JP2004516694A
Publication Date:
November 24, 2005
Filing Date:
June 26, 2003
Export Citation:
Assignee:
Medigene Oncologie Gezel Shaft Mitt Beschlenktel Haftung
International Classes:
A61K9/107; A61K9/127; A61K9/51; A61K31/335; A61K31/47; A61K31/4745; A61K47/10; A61K47/18; A61K47/24; A61K47/26; A61K47/28; A61K47/34; A61K47/36; A61K47/48; A61K49/18; A61P9/00; A61P35/00; C07D471/14; (IPC1-7): A61K31/4745; A61K9/107; A61K9/127; A61K9/51; A61K47/10; A61K47/18; A61K47/24; A61K47/26; A61K47/28; A61K47/34; A61K47/36; A61P9/00
Domestic Patent References:
| JP2001511807A | 2001-08-14 |
Foreign References:
| US5834012A | 1998-11-10 |
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard