Title:
Cancer antigen peptide endermic agent
Document Type and Number:
Japanese Patent JP6163486
Kind Code:
B2
Abstract:
An object of the present invention is to provide a transdermal preparation showing more efficient induction of CTL by a WT1 protein-derived cancer antigen peptide. The present invention enables more efficient CTL induction by applying a transdermal preparation containing a WT1 protein-derived cancer antigen peptide, and an ether-type additive represented by the formula (1):
R 1 -O-R 2 (1)
[wherein R 1 is a hydrocarbon group having 8 - 24 carbon atoms, and
R 2 is a group represented by the formula (2):
or a group represented by the formula (3):
-(CH 2 CH 2 O) m H(3)
wherein m is an integer of 1 - 18],
wherein the additive is liquid at 20°C, to a WT1 protein-derived cancer antigen peptide.
Inventors:
Masayasu Tanaka
Kazumi Yamamoto
Hiroo Maeda
Koichi Saito
Natsuko Sugibe
Kazumi Yamamoto
Hiroo Maeda
Koichi Saito
Natsuko Sugibe
Application Number:
JP2014523755A
Publication Date:
July 12, 2017
Filing Date:
July 02, 2013
Export Citation:
Assignee:
Sumitomo Dainippon Pharma Co., Ltd.
International Classes:
A61K39/00; A61K9/06; A61K9/08; A61K9/70; A61K47/10; A61K47/12; A61K47/18; A61K47/28; A61K47/34; A61P35/00
Domestic Patent References:
| JP2000212073A | ||||
| JP2011030981A | ||||
| JP2012501347A |
Foreign References:
| WO2009072610A1 | ||||
| WO2008108257A1 | ||||
| WO2009066462A1 | ||||
| WO2006118246A1 | ||||
| WO2010103845A1 |
Attorney, Agent or Firm:
Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Murata Miyuki
Junzo Koike
Hirofumi Toma
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Murata Miyuki
Junzo Koike
Hirofumi Toma