Title:
CANCER STEM CELL MARKERS AND USES THEREOF
Document Type and Number:
Japanese Patent JP2016047848
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a cancer stem cell marker and uses thereof.SOLUTION: The present invention inter alia pertains to therapeutic methods which are based on the use of an agent specifically binding a tumor-associated carbohydrate antigen for the treatment of cancer stem cells and related diseases. Also provided are diagnostic and prognostic methods using a tumor-associated carbohydrate antigen as a marker for cancer stem cells. According to a first aspect of the present invention, a binding agent is provided which specifically binds a tumor-associated carbohydrate antigen for use in the treatment of cancer stem cells expressing the tumor-associated carbohydrate antigen. Also provided is a pharmaceutical composition, comprising a respective binding agent for use in the treatment of cancer stem cells expressing the tumor-associated carbohydrate antigen.SELECTED DRAWING: None
Inventors:
GOLETZ STEFFEN
UWE KARSTEN
UWE KARSTEN
Application Number:
JP2015253064A
Publication Date:
April 07, 2016
Filing Date:
December 25, 2015
Export Citation:
Assignee:
GLYCOTOPE GMBH
International Classes:
A61K39/395; A61P35/00; A61P35/02; A61P35/04; C07K16/30; C07K16/46; C12M1/34; C12N5/095; C12N15/02; C12Q1/02; C12Q1/04; G01N33/48; G01N33/574
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita
Previous Patent: METHOD FOR PRODUCING INJECTABLE MEDICAMENT PREPARATION
Next Patent: SACHET FORMULATION FOR AMINE POLYMERS
Next Patent: SACHET FORMULATION FOR AMINE POLYMERS