CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION

Title:

CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION

Document Type and Number:

Japanese Patent JP2022097599

Kind Code:

A

Abstract:

To provide carbohydrate conjugated iRNA agents which are advantageous for the in vivo delivery of the iRNA agents.SOLUTION: The present invention provides carbohydrate conjugated iRNA agents which have improved purity and are advantageous for the in vivo delivery of the iRNA agents.SELECTED DRAWING: None

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Inventors:

NARAYANANNAIR K JAYAPRAKASH
ALEXANDER V KELIN
PACHAMUTHU KANDASAMY
RAJEEV G KALLANTHOTTATHIL
MUTHIAH MANOHARAN

Application Number:

JP2022076642A

Publication Date:

June 30, 2022

Filing Date:

May 06, 2022

Export Citation:

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Assignee:

ALNYLAM PHARMACEUTICALS INC

International Classes:

C07H21/02; A61K31/713; A61K47/26; A61K47/54; A61K48/00; A61P43/00; C07C231/02; C07C231/12; C07C235/08; C07D207/12

Domestic Patent References:

JP2011505425A

2011-02-24

Attorney, Agent or Firm:

Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe

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