Title:
ヒストンデアセチラーゼの新規な阻害剤としてのカルボニルアミノ誘導体
Document Type and Number:
Japanese Patent JP4648628
Kind Code:
B2
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, R5, L, Q, X, Y and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Inventors:
Van Emmelen, Christoph
Beldonck, Marc Gustav Serene
Van Brandt, Sfuen Franciscus Anna
Bax, Leo Jacobs Joseph
Beldonck, Marc Gustav Serene
Van Brandt, Sfuen Franciscus Anna
Bax, Leo Jacobs Joseph
Application Number:
JP2003574617A
Publication Date:
March 09, 2011
Filing Date:
March 11, 2003
Export Citation:
Assignee:
JANSSEN PHARMACEUTICA NAAMLOZE VENNOOTSCHAP
International Classes:
C07D211/58; C07D249/12; A61K31/40; A61K31/438; A61K31/4427; A61K31/4439; A61K31/444; A61K31/445; A61K31/4468; A61K31/451; A61K31/4545; A61K31/4709; A61K31/472; A61K31/4725; A61K31/495; A61K31/496; A61K31/497; A61K31/506; A61K31/517; A61K31/53; A61K31/5377; A61K31/55; A61K31/551; A61K45/00; A61P1/04; A61P3/10; A61P5/00; A61P9/00; A61P9/02; A61P9/08; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/08; A61P13/10; A61P13/12; A61P15/00; A61P17/00; A61P17/04; A61P17/06; A61P17/10; A61P17/14; A61P17/16; A61P19/02; A61P19/06; A61P21/04; A61P25/00; A61P25/16; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/18; A61P35/00; A61P35/02; A61P37/02; A61P37/04; A61P37/06; A61P37/08; A61P43/00; C07C259/10; C07D207/09; C07D207/14; C07D211/26; C07D213/74; C07D213/78; C07D217/02; C07D217/04; C07D239/42; C07D241/04; C07D295/14; C07D295/155; C07D295/20; C07D295/22; C07D295/26; C07D307/68; C07D317/58; C07D401/04; C07D401/06; C07D401/12; C07D401/14; C07D403/04; C07D403/12; C07D405/12; C07D405/14; C07D409/12; C07D413/02; C07D413/04; C07D413/12; C07D471/10; C12Q1/48
Domestic Patent References:
| JP56068669A | ||||
| JP58090552A | ||||
| JP47006026A | ||||
| JP47006025A |
Foreign References:
| WO2001038322A1 |
Other References:
Journal of Medicinal Chemistry,1974年,Vol.17, No.7,pp.739-744
応用薬理,1973年,Vol.7, No.7,pp.985-990
応用薬理,1973年,Vol.7, No.7,pp.985-990
Attorney, Agent or Firm:
Patent business corporation Odashima patent office