Title:
カルボン酸アミド、その化合物を含有する医薬組成物、その使用及び調製
Document Type and Number:
Japanese Patent JP5010788
Kind Code:
B2
Abstract:
Carboxylic acid amides of general formula which inhibit telomerase and are useful for treating tumor diseases such as carcinomas, sarcomas and leukaemias. Exemplary compounds are: (1) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-phenyl)-amide, and, (2) trans-3-(naphth-2-yl)-but-2-enoic acid-N-(2-carboxy-4,5-dimethoxy-phenyl)-amide.
Inventors:
Howell norbert
Prepke Henning
Dam Claus
Schnap Andreas
Prepke Henning
Dam Claus
Schnap Andreas
Application Number:
JP2001511906A
Publication Date:
August 29, 2012
Filing Date:
July 22, 2000
Export Citation:
Assignee:
Boehringer Ingelheim Pharma Gesellshaft Mitt Beschlenktel Haftung Und Company Comandito Gesellshaft
International Classes:
A61K31/16; C07C233/55; A61K31/165; C07D295/10; A61K31/167; A61K31/192; A61K31/194; A61K31/36; A61K31/381; A61K31/41; A61K31/415; A61K31/4164; A61K31/4184; A61K31/439; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/445; A61K31/4453; A61K31/4465; A61K31/47; A61K31/495; A61K31/5375; A61P35/00; A61P43/00; C07C233/46; C07C233/52; C07C233/63; C07C233/81; C07C235/38; C07C237/30; C07C237/42; C07C237/52; C07C239/20; C07C243/38; C07C255/24; C07C271/20; C07C271/28; C07C275/42; C07C309/51; C07C309/66; C07C311/08; C07C311/13; C07C311/21; C07C311/39; C07C311/46; C07C311/51; C07D207/20; C07D211/16; C07D211/26; C07D213/40; C07D213/53; C07D213/56; C07D213/75; C07D213/79; C07D215/48; C07D215/56; C07D231/12; C07D231/14; C07D231/38; C07D233/02; C07D233/26; C07D233/61; C07D233/88; C07D233/90; C07D235/06; C07D235/08; C07D257/04; C07D295/12; C07D295/155; C07D295/192; C07D295/22; C07D307/79; C07D311/06; C07D311/12; C07D311/20; C07D317/50; C07D317/68; C07D333/04; C07D333/36; C07D333/38; C07D333/40; C07D333/58; C07D333/60; C07D405/04; C07D487/04
Domestic Patent References:
| JPH0578315A | 1993-03-30 | |||
| JPH0672866A | 1994-03-15 | |||
| JPS60146855A | 1985-08-02 | |||
| JPS6097946A | 1985-05-31 | |||
| JPH1149676A | 1999-02-23 | |||
| JPH09154575A | 1997-06-17 | |||
| JPS4993335A | 1974-09-05 | |||
| JPS50140413A | 1975-11-11 | |||
| JPS60139646A | 1985-07-24 |
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Hideto Takeuchi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda