Title:
カルボン酸化合物およびその化合物を有効成分として含有する薬剤
Document Type and Number:
Japanese Patent JP5168315
Kind Code:
B2
Abstract:
A carboxylic acid compound represented by formula (I): (meanings of the symbols in the formula are as mentioned in the specification) and a pharmaceutical agent comprising the compound. Since the compound represented by formula (I) binds to a DP receptor and shows antagonistic activity for the DP receptor, it is useful for prevention and/or treatment of diseases such as allergic disease (such as allergic rhinitis, allergic conjunctivitis, atopic dermatitis, bronchial asthma and food allergy), systemic mastocytosis, disorders accompanied by systemic mast cell activation, anaphylaxis shock, bronchoconstriction, urticaria, eczema, diseases accompanied by itch (such as atopic dermatitis and urticaria), diseases (such as cataract, retinal detachment, inflammation, infection and sleeping disorders) which is generated secondarily as a result of behavior accompanied by itch (such as scratching and beating), inflammation, chronic obstructive pulmonary diseases, ischemic reperfusion injury, cerebrovascular accident, chronic rheumatoid arthritis, pleurisy, ulcerative colitis and the like.
Inventors:
Maki Iwahashi
Kaoru Kobayashi
Fumio Nanbu
Kaoru Kobayashi
Fumio Nanbu
Application Number:
JP2010105565A
Publication Date:
March 21, 2013
Filing Date:
April 30, 2010
Export Citation:
Assignee:
Ono Pharmaceutical Co., Ltd.
International Classes:
C07D265/36; A61P1/04; A61P7/00; A61P9/10; A61P11/00; A61P17/00; A61P25/06; A61P25/20; A61P29/00; A61P37/08; A61P43/00; C07D209/12; C07D307/80; C07D319/20; C07D327/06
Foreign References:
| WO1986005779A1 |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Masaru Nakajima