Title:
CARCINOSTATIC AGENT
Document Type and Number:
Japanese Patent JPS5767517
Kind Code:
A
Abstract:
NEW MATERIAL:N,N'-Tetramethylene-cis-epoxysuccinamide of formula.
USE: Carcinostatic agent having extremely low toxicity or almost free from toxicity, and nevertheless exhibiting strong carcinostatic effects.
PROCESS: The compound of formula is prepared by reacting a cis-epoxysuccinic acid dialkyl ester (e.g. cis-epoxysuccinic acid dimethyl ester) with nearly equimolar amount of 1,4-diaminobutane in a basic solvent such as pyridine, at 10W100°C.
Inventors:
YOSHITANI KIYOHIKO
MIURA YUUICHI
MIURA YUUICHI
Application Number:
JP14198480A
Publication Date:
April 24, 1982
Filing Date:
October 13, 1980
Export Citation:
Assignee:
TOKUYAMA SODA KK
International Classes:
C07D487/22; A61K31/395; A61P35/00; C07D491/044; (IPC1-7): A61K31/395; C07D491/044
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