CATALYTIC PRODUCTION METHOD FOR MONOFLUOROMETHYL SUBSTITUTED EPOXIDE VIA INACTIVE SP3C-F BOND ACTIVATION REACTION WITH SILICON REAGENT, AND MONOFLUOROMETHYL SUBSTITUTED EPOXIDE THEREOF

Title:

CATALYTIC PRODUCTION METHOD FOR MONOFLUOROMETHYL SUBSTITUTED EPOXIDE VIA INACTIVE SP3C-F BOND ACTIVATION REACTION WITH SILICON REAGENT, AND MONOFLUOROMETHYL SUBSTITUTED EPOXIDE THEREOF

Document Type and Number:

Japanese Patent JP2016034911

Kind Code:

A

Abstract:

PROBLEM TO BE SOLVED: To develop a catalytic synthesis technique for 2-fluoromethyl epoxide compounds by a strong carbon-fluorine bond cleavage reaction.SOLUTION: The inventors have developed a catalytic producing method for 2-fluoromethyl epoxide compounds by using a reaction of activating and cleaving a strong carbon-fluorine bond with a silicon reagent that strongly interacts with a catalytic amount of base and fluorine as the key reaction.SELECTED DRAWING: None

Inventors:

SHIBATA TETSUO
TANAKA JUNKI
TOKUNAGA ETSUKO

Application Number:

JP2014157623A

Publication Date:

March 17, 2016

Filing Date:

August 01, 2014

Export Citation:

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Assignee:

NAGOYA INST TECHNOLOGY

International Classes:

C07D301/26; B01J31/02; C07D303/08

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