カテプシンシステインプロテアーゼ阻害剤

Japanese Patent JP4201716

B2

This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

Bailey, Christopher Eye
Black, melon
Reggie, Sergey
Lii, Chiyun Shin
Matsukei, Dan
Melon, christophe
Gothie, Jack Eve
Lau, Chiyoku
Terian, Mitsuiel
Truong, Boy-Lin
Green, Michael Jay
Hershey Bain, Bernard El
The Yank, The James D'Abri
Palmer, James Tay
Bascaran, Chitra

JP2003574112A

December 24, 2008

February 28, 2003

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AXYS PHARMACEUTICALS, INC.

C07C311/16; C07D295/12; A61K31/275; A61K31/381; A61K31/404; A61K31/417; A61K31/42; A61K31/4245; A61K31/426; A61K31/427; A61K31/44; A61K31/4406; A61K31/4409; A61K31/4465; A61K31/47; A61K31/495; A61K31/505; A61K31/5375; A61K45/00; A61P1/02; A61P3/14; A61P19/02; A61P19/08; A61P19/10; A61P29/00; A61P35/00; A61P43/00; C07C255/25; C07C255/29; C07C255/46; C07C255/58; C07C255/60; C07C259/10; C07C311/37; C07C317/32; C07C317/36; C07D209/08; C07D211/26; C07D211/38; C07D213/36; C07D213/38; C07D213/57; C07D213/61; C07D213/64; C07D213/70; C07D213/71; C07D213/74; C07D213/89; C07D215/12; C07D231/12; C07D233/54; C07D233/64; C07D239/06; C07D239/26; C07D241/12; C07D261/08; C07D263/32; C07D271/06; C07D277/28; C07D295/135; C07D295/22; C07D307/52; C07D333/20; C07D401/04; C07D417/04

JP2001522862A
JP2001525804A
JP2001525809A

WO2002069901A1
WO1999059526A1

Yoshio Kawaguchi
Makoto Ono
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura
Akio Ichiiri
Makoto Ono

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