Title:
CCR9 INHIBITOR AND USE THEREOF
Document Type and Number:
Japanese Patent JP2011105725
Kind Code:
A
Abstract:
To provide a method for inhibiting CCR9 receptors.
A compound represented by the formula or a pharmaceutically acceptable salt, solvate or hydrate thereof is provided, wherein Y represents C(O), O, S, S(O) or S(O)2; X1, X2 and X3 represent each N or CR, wherein at least one of X1, X2 and X3 represents CR; R and R1 represent each H or a substituent; R6 represents H, an aliphatic carbonyl group or an aliphatic ester; the ring A may be substituted or non-substituted; Ar1 and Ar2 represent each a substituted or non-substituted aryl group or a substituted or non-substituted heteroaryl group.
Inventors:
FLEMING PAUL
HARRIMAN GERALDINE C B
SHI ZHAN
CHEN SHAOWU
HARRIMAN GERALDINE C B
SHI ZHAN
CHEN SHAOWU
Application Number:
JP2010265823A
Publication Date:
June 02, 2011
Filing Date:
November 29, 2010
Export Citation:
Assignee:
MILLENNIUM PHARM INC
International Classes:
A61K31/18; A61K31/381; A61K31/44; A61K31/4409; A61K31/4425; A61K31/444; A61K31/63; A61P1/04; A61P3/10; A61P5/14; A61P7/00; A61P9/00; A61P9/10; A61P13/12; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P21/00; A61P21/04; A61P25/28; A61P29/00; A61P37/06; A61P37/08; A61P43/00; C07C311/21; C07C311/29; C07C311/44; C07C311/46; C07C317/34; C07C321/30; C07C323/49; C07D213/30; C07D213/50; C07D213/65; C07D213/70; C07D213/71; C07D213/75; C07D213/76; C07D213/80; C07D213/89; C07D237/08; C07D239/26; C07D239/42; C07D333/34; C07D333/62; C07D405/06; C07D409/04; C07D409/06; C07D413/04; C07D413/14; C07D513/04
Domestic Patent References:
| JPH01156953A | 1989-06-20 |
Foreign References:
| WO2000053635A1 | 2000-09-14 |
Other References:
JPN6009016236; Ｅｕｒｏｐｅａｎ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ． ３７， Ｎｏ． ２, 200202, ｐ．１４７-１６１
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita