CDNA CLONE HAPOI67 ENCODING HUMAN 7-MEMBRANE-PENETRATIVE RECEPTOR

Title:

CDNA CLONE HAPOI67 ENCODING HUMAN 7-MEMBRANE-PENETRATIVE RECEPTOR

Document Type and Number:

Japanese Patent JPH1175869

Kind Code:

A

Abstract:

To obtain an HAPOI67 polypeptide useful for treating and diagnosing such diseases as infectious diseases caused by HIV-1 or HIV-2, pain, cancer, anorexia, overeating, asthma and Parkinson's disease, and to obtain a polynucleotide encoding the above polypeptide.

This HAPOI67 polypeptide includes an amino acid sequence ≥80% identical with an amino acid sequence of the formula; and the other objective polynucleotide includes a nucleotide sequence encoding a polypeptide ≥80% identical with the whole length of a nucleotide sequence encoding the above-mentioned polypeptide and having the activity of the HAPOI67 polypeptide, or a nucleotide sequence complementary to the above-mentioned nucleotide sequence. The polypeptide of the present invention can be recombinantly produced from the polynucleotide of the other present invention afforded by expression sequence tag analysis from a cDNA library derived from mRNA included in human splenocytes by the standard cloning and screening technique.

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Inventors:

SATHE GANESH MADHUSUDAN
MAO JOYCE YUE

Application Number:

JP16236498A

Publication Date:

March 23, 1999

Filing Date:

June 10, 1998

Export Citation:

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Assignee:

SMITHKLINE BEECHAM CORP

International Classes:

A61K31/70; A61K31/711; A61K38/00; A61K39/00; A61K45/00; A61K48/00; A61P1/04; A61P3/00; A61P7/10; A61P9/00; A61P9/02; A61P9/04; A61P9/08; A61P9/10; A61P9/12; A61P11/00; A61P11/06; A61P15/00; C12N15/09; A61P19/10; A61P25/00; A61P25/14; A61P25/16; A61P25/18; A61P25/22; A61P25/24; A61P25/28; A61P29/00; A61P31/00; A61P31/04; A61P31/12; A61P31/18; A61P33/02; A61P35/00; A61P37/08; C07K14/705; C07K16/28; C12N1/15; C12N1/19; C12N1/21; C12N5/00; C12N5/10; C12N15/12; C12P21/02; C12P21/08; C12Q1/02; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/566; G01N33/577; G01N33/68; C12R1/91; (IPC1-7): C12N15/09; A61K31/70; A61K38/00; A61K45/00; A61K48/00; C07K14/705; C12N5/10; C12P21/02; C12P21/08; G01N33/15; G01N33/50; G01N33/53; G01N33/566; G01N33/577

Attorney, Agent or Firm:

Yusuke Hiraki (2 outside)

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