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Title:
細胞接着阻害抗炎症および免疫抑制化合物
Document Type and Number:
Japanese Patent JP2004513063
Kind Code:
A
Abstract:
The present invention relates to cinnamide compounds of formula (I), in which at least one of R1 to R5 is a "cis-cinnamide" (a) or a "trans-cinnamide" (b) and the other variables are as defined in the claims, that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds and to methods of inhibiting inflammation or suppressing immune response in a mammal.

Inventors:
Link, james
Riu, Gun
Pay, zombie
Bon Geldern, Thomas W.
Win, martin
Shin, Tree
One, Sheldon
Boyd, Stephen A.
Chu, gui-don
Freeman, Jennifer C.
Gunawadana, Indra Niw.
Stiger, Michael A.
Je, Hwan-Saw
Lynch, John Kay.
Application Number:
JP2000609392A
Publication Date:
April 30, 2004
Filing Date:
April 03, 2000
Export Citation:
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Assignee:
ABBOTT LABORATORIES
International Classes:
A61K31/10; A61K31/165; A61K31/33; A61K31/40; A61K31/4015; A61K31/41; A61K31/417; A61K31/438; A61K31/44; A61K31/4427; A61K31/445; A61K31/4468; A61K31/451; A61K31/453; A61K31/454; A61K31/4545; A61K31/472; A61K31/496; A61K31/4965; A61K31/506; A61K31/5375; A61K31/5377; A61K31/54; A61K31/541; A61K31/55; A61K31/551; A61P29/00; A61P37/06; C07C323/60; C07C323/62; C07D205/04; C07D207/09; C07D207/12; C07D207/14; C07D207/16; C07D207/26; C07D207/27; C07D207/273; C07D209/08; C07D209/12; C07D211/20; C07D211/22; C07D211/46; C07D211/60; C07D211/62; C07D211/64; C07D211/66; C07D211/70; C07D213/40; C07D213/74; C07D213/81; C07D215/24; C07D217/02; C07D217/04; C07D217/06; C07D233/61; C07D239/42; C07D243/08; C07D241/04; C07D241/24; C07D257/04; C07D279/12; C07D295/18; C07D295/185; C07D295/20; C07D295/205; C07D295/22; C07D295/26; C07D307/24; C07D307/52; C07D307/68; C07D317/58; C07D317/66; C07D319/18; C07D401/04; C07D401/12; C07D405/12; C07D417/12; C07D471/20; C07D487/04; C07D491/113; C07D521/00; A61K; A61P; C07C; C07D; (IPC1-7): C07C323/60; A61K31/40; A61K31/4015; A61K31/41; A61K31/417; A61K31/438; A61K31/44; A61K31/4427; A61K31/445; A61K31/4468; A61K31/451; A61K31/453; A61K31/454; A61K31/4545; A61K31/472; A61K31/496; A61K31/4965; A61K31/506; A61K31/5375; A61K31/5377; A61K31/54; A61K31/541; A61K31/55; A61K31/551; A61P29/00; A61P37/06; C07C323/62; C07D207/12; C07D207/27; C07D207/273; C07D209/08; C07D209/12; C07D211/22; C07D211/60; C07D211/62; C07D211/64; C07D211/66; C07D211/70; C07D213/74; C07D215/24; C07D217/04; C07D233/61; C07D239/42; C07D241/24; C07D243/08; C07D257/04; C07D279/12; C07D295/18; C07D295/20; C07D295/22; C07D307/24; C07D307/52; C07D317/58; C07D319/18; C07D401/04; C07D401/12; C07D405/12; C07D417/12; C07D471/20; C07D487/04; C07D491/113
Attorney, Agent or Firm:
Aoyama Aoi
Kyousei Tamura