Title:
CELL ADHESION MOLECULE
Document Type and Number:
Japanese Patent JPH04311396
Kind Code:
A
Abstract:
PURPOSE: To provide a new polypeptide to be bound to a monoclonal antibody to give a new integrin glycopeptide complex controlled by a cell-cell interaction and useful for regulating imunoresponse such as inflammation.
CONSTITUTION: This cell adhesion molecule is a purified polypeptide comprising a gp98 fragment having an amino acid sequence comprising gp98 and at least 5 adjoining amino acids in the amino acid sequence of gp98. The polypeptide is preferably produced by integrating a DNA expressing the above polypeptide constructed from a cDNA library separated material coding gp98 into a vector, transforming a host cell with said vector and allowing the transformant to produce the polypeptide.
Inventors:
JIYOSEFU EICHI FUIRITSUPUSU
RISA MATSUKINNII
RUISU ERU RANIAA
RISA MATSUKINNII
RUISU ERU RANIAA
Application Number:
JP24348091A
Publication Date:
November 04, 1992
Filing Date:
September 24, 1991
Export Citation:
Assignee:
BECTON DICKINSON CO
International Classes:
C07K1/22; C07K14/00; C07K14/705; C07K16/00; C07K16/28; C12N5/10; C12N15/02; C12P21/00; C12P21/08; G01N33/53; A61K38/00; C12R1/91; (IPC1-7): C07K15/14; C12N5/20; C12N15/06; C12P21/00; C12P21/08; G01N33/53
Attorney, Agent or Firm:
Kyozo Yuasa (5 people outside)
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