Title:
細胞情報取得方法および細胞情報取得装置
Document Type and Number:
Japanese Patent JP6948778
Kind Code:
B2
Abstract:
A cell information acquisition method may include: binding a binding substance to a receptor on a cell membrane surface of a cell, the binding substance being bindable to the receptor; permeabilizing a cell membrane of the cell after the binding; labeling a receptor in an intracellular area of the cell with a binding substance labeled with a first labeling substance after the permeabilizing; causing a specimen including the cell to flow through a flow path after the labeling; irradiating the cell included in the specimen flowing through the flow path with light; and acquiring a signal based on light generated from the first labeling substance in the cell irradiated with light.
Inventors:
Keiko Yoshikawa
Yuma Oka
Fujiyama Shingo
Yuma Oka
Fujiyama Shingo
Application Number:
JP2016210088A
Publication Date:
October 13, 2021
Filing Date:
October 26, 2016
Export Citation:
Assignee:
Sysmex Corporation
International Classes:
G01N33/53; G01N21/78; G01N33/48; G01N33/543
Domestic Patent References:
| JP8313528A | ||||
| JP2005315862A |
Foreign References:
| US20150374845 |
Other References:
N L.CARRODUS, et al.,Differential Labeling of Cell-surface and Internalized Proteins after Antibody Feeding of Live Cultured Neurons,Journal of Visualized Experiments,2014年,Vol.84, e51139,Page.1-6
Attorney, Agent or Firm:
Masamasa Shibano