間葉系幹細胞を含む細胞集団とその製造方法、間葉系幹細胞及び医薬組成物

Japanese Patent JP7152389

B2

The present invention addresses the problem of providing a cell population which includes mesenchymal stem cells having a strong immunosuppressive effect, a production method therefor, mesenchymal stem cells having a strong immunosuppressive effect, and a pharmaceutical composition which includes the cell population. The present invention provides a production method for a cell population which includes mesenchymal stem cells, wherein the production method involves obtaining a cell population having the following cell characteristics indicated in (a) and (b): (a) the ratio of mesenchymal stem cells which are positive for CD97 in the cell population is 30% or higher, and (b) the cell population includes mesenchymal stem cells which are positive for CD358.

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Keita Inao
Yuta Kida

JP2019511269A

October 12, 2022

April 03, 2018

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Kaneka Corporation

C12N5/0775

WO2015025810A1
WO2013077428A1
WO2017025729A1

Human Reproduction,2008年,Vol. 23, No. 8,pp. 1760-1770
TISSUE ENGINEERING: Part A,2011年,Vol. 17, Nos. 9 and 10,pp. 1375-1388

Hiraki International Patent Office

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