Title:
セファロマンニン誘導体、その製法と他の薬物組成物及び用途
Document Type and Number:
Japanese Patent JP2011503121
Kind Code:
A
Abstract:
The present invention discloses cephalomannine derivatives of general formula (I), a process for preparation of such cephalomannine derivatives, a composition containing such compounds, and use of said compounds in the manufacture of a medicament for the treatment of tumors, especially multidrug resistant tumors.
Inventors:
Katayu
Chen Xiaoming
Yang Chun Go
Lee
Hongbo Wang
Liu Hongyan
Hankyu
Zhao Satoshi
Chen Xiaoming
Yang Chun Go
Lee
Hongbo Wang
Liu Hongyan
Hankyu
Zhao Satoshi
Application Number:
JP2010533407A
Publication Date:
January 27, 2011
Filing Date:
November 15, 2007
Export Citation:
Assignee:
Chinese Academy of Medical Sciences
International Classes:
C07D305/14; A61K31/337; A61P35/00
Domestic Patent References:
| JP2003521545A | 2003-07-15 |
Other References:
JPN6012058160; ＹＡＮＧ，Ｃ． ｅｔ ａｌ: 'Ｏｖｅｒｃｏｍｉｎｇ ｔｕｍｏｒ ｄｒｕｇ ｒｅｓｉｓｔａｎｃｅ ｗｉｔｈ ｈｉｇｈ-ａｆｆｉｎｉｔｙ ｔａｘａｎｅｓ： ａ ＳＡＲ ｓｔｕｄｙ ｏｆ Ｃ２-ｍｏｄｉｆｉｅｄ ７-ａｃｙｌ-１０-ｄｅ' ＣｈｅｍＭｅｄＣｈｅｍ Ｖｏｌ．２， Ｎｏ．５, 20070514, ｐ．６９１-７０１
JPN7012004532; ＪＡＧＴＡＰ，Ｐ．Ｇ． ｅｔ ａｌ: 'Ｄｅｓｉｇｎ ａｎｄ Ｓｙｎｔｈｅｓｉｓ ｏｆ ａ Ｃｏｍｂｉｎａｔｏｒｉａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｉｂｒａｒｙ ｏｆ ７-Ａｃｙｌ， １０-Ａｃｙｌ， ａｎｄ ７，１０-Ｄｉａｃｙｌ Ａｎａｌｏｇ' Ｊｏｕｒｎａｌ ｏｆ Ｎａｔｕｒａｌ Ｐｒｏｄｕｃｔｓ Ｖｏｌ．６５， Ｎｏ．８, 2002, ｐ．１１３６-１１４２
JPN7012004532; ＪＡＧＴＡＰ，Ｐ．Ｇ． ｅｔ ａｌ: 'Ｄｅｓｉｇｎ ａｎｄ Ｓｙｎｔｈｅｓｉｓ ｏｆ ａ Ｃｏｍｂｉｎａｔｏｒｉａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｉｂｒａｒｙ ｏｆ ７-Ａｃｙｌ， １０-Ａｃｙｌ， ａｎｄ ７，１０-Ｄｉａｃｙｌ Ａｎａｌｏｇ' Ｊｏｕｒｎａｌ ｏｆ Ｎａｔｕｒａｌ Ｐｒｏｄｕｃｔｓ Ｖｏｌ．６５， Ｎｏ．８, 2002, ｐ．１１３６-１１４２
Attorney, Agent or Firm:
Kenzo Hara International Patent Office