Title:
CHANGING EYE COLOR BY GENE TRANSDUCTION
Document Type and Number:
Japanese Patent JP2023171654
Kind Code:
A
Abstract:
To provide change of an eye color by gene transduction.SOLUTION: A person's iris color can be lightened, e.g., from brown to lighter brown, green, hazel or blue, by introducing a melanocyte-killing agent through the cornea of the person's eye and contacting the anterior surface of the iris with the agent at a dose sufficient to kill melanocytes in the iris stroma. In one aspect, the disclosure provides a composition for changing a color of a subject's iris, comprising a sterile ophthalmic preparation comprising a genetic vector carrying (a) a suicide gene and (b) a melanocyte-specific gene promoter operably linked to the suicide gene.SELECTED DRAWING: None
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Inventors:
JAMES W HILL
Application Number:
JP2023177462A
Publication Date:
December 01, 2023
Filing Date:
October 13, 2023
Export Citation:
Assignee:
JAMES W HILL
International Classes:
A61K48/00; A61K31/522; A61K35/76; A61K35/761; A61P27/02; A61P43/00
Attorney, Agent or Firm:
Shusaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto