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Title:
化学感覚受容体リガンドに基づく治療法
Document Type and Number:
Japanese Patent JP2014501787
Kind Code:
A
Abstract:
Provided herein are methods for treating conditions associated with a chemosensory receptor, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a chemosensory receptor ligand, such as a bitter receptor ligand. Also provided herein are chemosensory receptor ligand compositions, including bitter receptor ligand compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use.

Inventors:
Baron Aligned.
Brown Martin Earl.
Jones Christopher Earl G.
Bealey Nigel Earl A.
Feynman Mark S.
Application Number:
JP2013548591A
Publication Date:
January 23, 2014
Filing Date:
January 06, 2012
Export Citation:
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Assignee:
Elcerix Therapeutics, Inc.
International Classes:
A61K31/122; A61K31/04; A61K31/045; A61K31/05; A61K31/12; A61K31/125; A61K31/135; A61K31/155; A61K31/165; A61K31/19; A61K31/192; A61K31/341; A61K31/353; A61K31/355; A61K31/36; A61K31/365; A61K31/381; A61K31/40; A61K31/417; A61K31/4172; A61K31/437; A61K31/4375; A61K31/445; A61K31/4525; A61K31/455; A61K31/472; A61K31/475; A61K31/4965; A61K31/505; A61K31/51; A61K31/52; A61K31/551; A61K31/575; A61K31/58; A61K31/7004; A61K31/7012; A61K31/7016; A61K31/704; A61K31/7048; A61K33/24; A61K36/00; A61K36/18; A61K36/23; A61K36/25; A61K36/28; A61K36/42; A61K36/47; A61K36/48; A61K36/53; A61K36/60; A61K36/70; A61K36/73; A61K36/75; A61K36/896; A61K45/00; A61K47/04; A61K47/10; A61K47/12; A61K47/24; A61K47/44; A61K47/46; A61P1/04; A61P1/10; A61P1/14; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P15/00; A61P19/10; A61P21/00
Domestic Patent References:
JP2005508331A2005-03-31
JP2008533127A2008-08-21
JP2010508041A2010-03-18
JP2002529504A2002-09-10
JPH08143476A1996-06-04
Foreign References:
WO2006086727A22006-08-17
WO2010123930A22010-10-28
CN101190179A2008-06-04
KR20070045940A2007-05-02
CN1891229A2007-01-10
US20100184796A12010-07-22
US20080038739A12008-02-14
US20100267643A12010-10-21
US20100254916A12010-10-07
Other References:
橋田充 編, 経口投与製剤の設計と評価, JPN6017030020, 1995, pages 259 - 261, ISSN: 0003761937
THE JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 57, no. 5, JPN6015043610, 2005, pages 565 - 571, ISSN: 0003618037
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto