Title:
ホスホジエステラーゼ10阻害剤としてのシンノリン及びキナゾリン誘導体
Document Type and Number:
Japanese Patent JP2009528365
Kind Code:
A
Abstract:
The present invention if directed to certain cinnoline compounds that are PDE10 inhibitors, pharmaceutical compounds containing the same and processes for preparing the same. The invention is also directed to methods of treating diseases mediated by PDE10 enzyme such as obesity, non-insulin dependent diabetes, schizophrenia or bipolar disorder, obsessive-compulsive disorder, and the like.
Inventors:
Stephen Ah.
Marc P. Allington
Arlen Tea. Hopper
Richard D. Contissero
Hans-Jurgen Jesus
Marc P. Allington
Arlen Tea. Hopper
Richard D. Contissero
Hans-Jurgen Jesus
Application Number:
JP2008557360A
Publication Date:
August 06, 2009
Filing Date:
February 27, 2007
Export Citation:
Assignee:
Amgen Incorporated
Memory Pharmaceuticals Corporation
Memory Pharmaceuticals Corporation
International Classes:
A61K31/502; C07D237/28; A61K31/506; A61K31/5377; A61P25/18; A61P25/22; A61P25/24; A61P43/00; C07D401/04; C07D401/14; C07D403/04; C07D403/10; C07D405/04; C07D413/04; C07D413/10; C07D417/04; C07D471/04
Attorney, Agent or Firm:
Toru Ishikawa