Title:
心房細動の評価における循環ＢＭＰ１０（骨形成タンパク質１０）
Document Type and Number:
Japanese Patent JP7232434
Kind Code:
B2
Abstract:
The present invention relates to a method for assessing atrial fibrillation in a subject, said method comprising the steps of determining the amount of BMP 10 in a sample from the subject, and comparing the amount of BMP 10 to a reference amount, whereby atrial fibrillation is to be assessed. Moreover, the present invention relates to a method for diagnosing heart failure based on the determination of BMP 10 in a sample from a subject. Further, the present invention relates to a method for predicting the risk of a subject of hospitalization due to heart failure based on the determination of a BMP 10-type peptide in a sample from a subject.
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Inventors:
Carl, Johann
Kastner, Peter
Bean Hughes-Terren, Ursula-Henrique
Dietrich, Manuel
Ziegler, Andre
Schotten, Ulrich
Kastner, Peter
Bean Hughes-Terren, Ursula-Henrique
Dietrich, Manuel
Ziegler, Andre
Schotten, Ulrich
Application Number:
JP2021532521A
Publication Date:
March 03, 2023
Filing Date:
August 16, 2019
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
ACADEMISCH ZIEKENHUIS MAASTRICHT
ACADEMISCH ZIEKENHUIS MAASTRICHT
International Classes:
G01N33/53
Domestic Patent References:
| JP2012526087A | ||||
| JP2018518461A |
Foreign References:
| WO2018024905A1 |
Other References:
SYEDA, F. et al.,PITX2-dependent gene regulation in atrial fibrillation and rhythm control,The Journal of Physiology,2017年,Vol.595, No.12,p.4019-4026
TESSARI, A. et al.,Myocardial Pitx2 Differentially Regulates the Left Atrial Identity and Ventricular Asymmetric Remodeling Programs,Circulation Research,2008年,Vol.102, No.7,p.813-822
TESSARI, A. et al.,Myocardial Pitx2 Differentially Regulates the Left Atrial Identity and Ventricular Asymmetric Remodeling Programs,Circulation Research,2008年,Vol.102, No.7,p.813-822
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Junichi Matsuo
Yukiko Kunieda
Toru Miyamae
Junichi Matsuo
Yukiko Kunieda
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