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Title:
生理活性な異種ドメインを担持するコラーゲン線維およびその、例えば、創傷の治癒における使用
Document Type and Number:
Japanese Patent JP2007527204
Kind Code:
A
Abstract:
A modified pro-± chain comprising a triple helix forming domain linked to at least an N-terminal domain, the N-terminal domain containing a polypeptide from at least part of a laminin glycoprotein or secretory leukocyte protease inhibitor. The pro-± chain may form part of a procollagen molecule that has the N-terminal domain retained. The procollagen molecules may be incorporated into collagen polymers, matrices and gels and be used for such applications as wound healing.

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Inventors:
Karl Quadler
Neil Blade
Gillian Ashcroft
Application Number:
JP2006506159A
Publication Date:
September 27, 2007
Filing Date:
April 21, 2004
Export Citation:
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Assignee:
THE UNIVERSITY OF MANCHESTER
International Classes:
C12N15/09; A61K38/00; A61K38/17; A61K38/55; A61K48/00; A61L15/16; A61L15/32; A61L27/00; A61L27/22; A61L27/24; A61L27/60; A61P11/00; A61P17/02; A61P19/02; A61P43/00; C07K14/78; C07K14/81; C07K19/00; C12N15/62
Domestic Patent References:
JP2000125872A2000-05-09
JP2001518518A2001-10-16
Foreign References:
WO2003016907A12003-02-27
Attorney, Agent or Firm:
Mitsuo Tanaka
Tadayuki Motoyama
Kenji Tomita



 
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