COLORING AGENTS FOR FLUORESCENT NUCLEIC ACID

Title:

COLORING AGENTS FOR FLUORESCENT NUCLEIC ACID

Document Type and Number:

Japanese Patent JPS56158944

Kind Code:

A

Abstract:

Nucleic acids in a biological sample are detected by staining said acids with a fluorescent dye of the formula: wherein n represents an integer having a value of 0 or 1; m represents an integer having a value of 1 or 2; R represents a member selected from the group consisting of an alkyl radical having 1 to 4 carbon atoms which may be substituted with dialkylamino having 1-4 carbon atoms in the alkyl moieties; R1 and R2 each represent members selected from the group consisting of hydrogen, lower alkyl and halo substituted lower alkyl; R3 represents a member selected from the group consisting of hydrogen, lower alkyl, lower alkoxy and amino; Z represents the nonmetallic atoms necessary to complete a heterocyclic nucleus selected from the group consisting of a benzothiazole nucleus, indolenine nucleus, naphthothiazole nucleua, benzoselenazole nucleus, benzoxazole nucleus, quinoline nucleus, and pyridine nucleus any of which may be substituted with lower alkyl, halo, nitro, and dialkyl amino; and X represents an anion.s

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Inventors:

CHIYAOOUEI JIEFURII UONGU
MAIKERU AANESUTO JIYOREI

Application Number:

JP5446381A

Publication Date:

December 08, 1981

Filing Date:

April 13, 1981

Export Citation:

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Assignee:

ABBOTT LAB

International Classes:

G01N33/52; C09B23/00; C12Q1/68; G01N33/48; G01N33/50; (IPC1-7): C09B23/14; G01N33/50

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