To provide an analytical system which makes use of a polyacetylene membrane, which can be used universally, by which various organism samples can be analyzed simply and with high sensitivity and in which the membrane can be manufactured easily.
A coloring sensor is formed in such a way that it is composed of fine particles covered with a polydiacetylene membrane liposome, with a polyacetylene membrane film or with a polydiacetylene membrane and that proteins whose molecule is made low are taken into the polydiacetylene membrane so as not to generate a hue change in the membrane. An analytical method uses the sensor. As a preferable state, the proteins whose molecule is made low are formed in such a way that an antibody Fab' fragment, an antigen protein having a molecular weight of 100000 or lower, a peptide which is composed of the residual group of 3 to 20 pieces of amino acids or single-stranded DNA having 100 bases or lower used to form double-stranded DNA by hybridization with single-stranded DNA in a sample and an antibody which reacts with the double-stranded DNA and which does not react with the single-stranded DNA are combined. The hue change of the polydiacetylene membrane is generated by an antigen-antibody reaction with an analyte (a component to be inspected) in the sample, and the analyte can be analyzed with high sensitivity.
| JP3170241 | NUCLEOTIDE REAGENT |
| JPS5655199 | DETERMINATION OF HYDROGEN PEROXIDE |
| WO/2013/081946 | PLAQUE ARRAY METHOD AND COMPOSITIONS FOR FORMING AND DETECTING PLAQUES |
INOUE TOSHIKI
TAKADA KOICHI
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