Title:
ペンタアザ大環状環複合体による組み合わせ癌免疫療法
Document Type and Number:
Japanese Patent JP7270235
Kind Code:
B2
Abstract:
A method of treating a cancer in a mammalian subject afflicted with the cancer, includes administering to the subject an immune checkpoint inhibitor, and administering to the subject a pentaaza macrocyclic ring complex corresponding to the formula (I) below, prior to, concomitantly with, or after administration of the immune checkpoint inhibitor, to increase the response of the cancer to the immune checkpoint inhibitor.
Inventors:
Robert A. Beardsley
Jeffrey El Keene
Dennis P. Riley
Jeffrey El Keene
Dennis P. Riley
Application Number:
JP2017081304A
Publication Date:
May 10, 2023
Filing Date:
April 17, 2017
Export Citation:
Assignee:
GALERA LABS, LLC
International Classes:
A61K39/395; A61K31/555; A61K45/00; A61P35/00; A61P43/00
Foreign References:
| US20110136756 |
Other References:
Crinical Reviews in Oncology/Hematology,2017年03月07日,Vol.113,P.63-70
nature reviews cancer,2012年,Vol.12,P.252-264
nature reviews cancer,2012年,Vol.12,P.252-264
Attorney, Agent or Firm:
Yamato Kento
Wu Yingyan
Wataru Sato
Shinagawa
Wu Yingyan
Wataru Sato
Shinagawa
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